Tuesday 29 July 2008

Blood Pressure Drug Dementia Hope

A drug used to lower blood pressure could prevent or delay thousands of Alzheimer's cases, US research has suggested.

 

People taking angiotensin receptor blockers were up to 40% less likely to develop dementia than those taking other blood pressure drugs.

 

And patients already suffering from dementia were less likely to get worse.

 

The number of people in the UK with dementia is expected to soar to 1.7 million over the next two decades.

 

This could mean an enormous extra burden for families and the taxpayer, but the Boston University School of Medicine Research, presented at a conference in Chicago, suggests there could be ways to prevent it.

 

High blood pressure over long periods can lead to damaged blood vessels, and is known to increase the risk of not only strokes and heart disease, but dementia as well.

 

Some types of dementia are directly related to the condition of the arteries supplying the brain, but blood pressure is also thought to play a role in Alzheimer's disease, which is linked to the appearance of protein deposits in brain tissue.

 

However, the reasons for this are not clear.

 

Symptom delay

 

The research looked at records of approximately six million people treated for high blood pressure between 2001 and 2006.

 

Those who took angiotensin receptor blockers (ARBs) were less likely, over that period, to be diagnosed with dementia compared with those on other blood pressure medication such as ACE inhibitors.

 

If they already had dementia in 2001, they were 45% less likely to go on to develop delirium, be admitted to a nursing home, or die prematurely.

 

This evidence suggests that the drugs, which help prevent the constriction of blood vessels, could not only prevent, or at least delay, the arrival of dementia symptoms, but also slow down the progress of the disease.

 

ARBs are normally prescribed only to patients who cannot tolerate ACE inhibitors.

 

Professor Clive Ballard, from the Alzheimer's Society, said that full clinical trials, following a smaller number of patients over a longer period, were now needed.

 

"High blood pressure doubles the risk of Alzheimer's disease and increases risk of stroke - this study highlights that it is becoming increasingly important to investigate blood pressure lowering drugs as a potential treatment for dementia.

 

"These findings will be important in stimulating further research into the relationship between anti-hypertension drugs and the development of dementia."

 

(Source:  http://news.bbc.co.uk/2/hi/health/7528539.stm)



1 comment:

Michael said...

High Blood Pressure Dieting- 5 Free Tips

1. Sodium is often one major cause of high blood pressure. Therefore, our doctor and researchers suggest you reduce your sodium intake to 2,300 milligrams a day. The recommended daily allowance for sodium is 2,400 milligrams a day in the United States. Begin to look at labels.

2. Reduction of meat consumption would also be recommended. If you have to splurge, try to keep it to lean meats including chicken, turkey and fresh fish. Remember that many packaged fish are preserved with sodium.

3. Fresh fruits and vegetable with greatly aid in you high blood pressure dieting. Always stick with fresh, raw fruits and vegetables throughout the day. Be daring and eat a variety of fruit with a variety of color. We would recommend at least 7 servings per day.

4. Try adding to your diet: nuts; seeds, dried beans, and whole grains. This is a nutritious way to get your body the nutrients it needs but also a good way to drop some HBP points.

5. Watch the fat! Fat usually equals cholesterol, saturated fat, trans fat and many high blood pressure ingredients. Try to keep the fat intake to 60 grams per day. Always avoid the unhealthy fast food restaurants because of the temptation to splurge.